The world has surpassed three million deaths from COVID-19, and faces potentially catastrophic tipping points in the global climate system. Despite the urgency, governments have struggled to address either problem. In this paper, we argue that COVID-19 and anthropogenic climate change (ACC) are critical examples of an emerging type of governance challenge: severe collective action problems that require significant individual behavior change under conditions of hyper- partisanship and scientific misinformation. Building on foundational political science work demonstrating (...) the potential for norms (or informal rules of behavior) to solve collective action problems, we analyze more recent work on norms from neighboring disciplines to offer novel recommendations for more difficult challenges like COVID-19 and ACC. Key insights include more attention to (1) norm-based messaging strategies that appeal to individuals across the ideological spectrum or that reframe collective action as consistent with resistant subgroups’ pre-existing values, (2) messages that emphasize both the prevalence and the social desirability of individual behaviors required to address these challenges, (3) careful use of public policies and incentives that make individual behavior change easier without threatening norm internalization, and (4) greater attention to epistemic norms governing trust in different information sources. We conclude by pointing out that COVID-19 and climate change are likely harbingers of other polarized collective action problems that governments will face in the future. By connecting work on norms and political governance with a broader, interdisciplinary literature on norm psychology, motivation, and behavior change, we aim to improve the ability of political scientists and policy makers to respond to these and future collective action challenges. (shrink)

As the economy has grown increasingly financialized, the relationship between financial innovation and instability has attracted more attention. Previous research finds that the proliferation of complex financial innovations, like asset securitization and new financial derivatives, helped to erode the market governance arrangements that kept excessive bank risk-taking in check, inviting instability. This article presents an alternative way of understanding how financial innovations and market governance arrangements combine to shape instability. Market governance arrangements also shape how financial firmsreceiveinnovations, (...) leading to greater or lesser instability at particular times and places. I illustrate this argument by tracing the effects of changing corporate governance arrangements at large US banks in the 1990s and 2000s. Like non-financial firms in the preceding decade, banks adopted reforms associated with the shareholder value model of corporate governance. These changes to internal bank governance arrangements affected the agendas of bank executives in ways that encouraged expanded use of securitization and derivatives. Drawing from this case, I argue that a full understanding of instability in the financialized era requires closer attention to the (institutionally-structured) interests of financial innovationusers—not just to features of financial innovations themselves. (shrink)

The most powerful lesson learned from the 2013-2016 outbreak of Ebola in West Africa was that we do not learn our lessons. A common sentiment at the time was that Ebola served as a “wake-up call”—an alarm which signalled that an outbreak of that magnitude should never have occurred and that we are ill-prepared globally to prevent and respond to them when they do. Pledges were made that we must learn from the outbreak before we were (...) faced with another. Nearly five years later the world is in the grips of a pandemic of the severe acute respiratory syndrome coronavirus 2 that causes coronavirus disease 2019. It is therefore of no surprise that we are now yet again hearing that the COVID-19 pandemic serves as the “wake-up call” we need and that there are many lessons to be learned to better prepare us for future outbreaks. Will anything be different this time around? We argue that nothing will fundamentally change unless we truly understand and appreciate the nature of the lessons we should learn from these outbreaks. Our past failures must be understood as moral failures that offer moral lessons. Unless we appreciate that we have a defect in our collective moral attitude toward remediating the conditions that precipitate the emergence of outbreaks, we will never truly learn. (shrink)

We examine the relationship between corporate governance and the extent of corporate social responsibility (CSR) disclosures in the annual reports of Bangladeshi companies. A legitimacy theory framework is adopted to understand the extent to which corporate governance characteristics, such as managerial ownership, public ownership, foreign ownership, board independence, CEO duality and presence of audit committee influence organisational response to various stakeholder groups. Our results suggest that although CSR disclosures generally have a negative association with managerial ownership, such relationship (...) becomes significant and positive for export-oriented industries. We also find public ownership, foreign ownership, board independence and presence of audit committee to have positive significant impacts on CSR disclosures. However, we fail to find any significant impact of CEO duality. Thus, our results suggest that pressures exerted by external stakeholder groups and corporate governance mechanisms involving independent outsiders may allay some concerns relating to family influence on CSR disclosure practices. Overall, our study implies that corporate governance attributes play a vital role in ensuring organisational legitimacy through CSR disclosures. The findings of our study should be of interest to regulators and policy makers in countries which share similar corporate ownership and regulatory structures. (shrink)

While corporate failures, such as Enron and WorldCom, have focused attention on issues of business ethics, corporate governance and risk management, there is nothing intrinsically new in the reasons behind their collapse. Neither is there anything fresh in the media's rush to identify a scapegoat. An examination of the financial collapse of Mirror Group Newspapers and Barings Bank, demonstrates failures within both these companies' corporate cultures and management systems, which allowed, if not encouraged, unethical behaviour by key individuals. It (...) is argued that a combination of legislation, regulation, effective risk management and appropriate sanctions are needed, if such unethical behaviour, and resulting corporate failure, is to be prevented in future. (shrink)

The exercise of identifying lessons in the aftermath of a major public health emergency is of immense importance for the improvement of global public health emergency preparedness and response. Despite the persistence of the Ebola Virus Disease outbreak in West Africa, it seems that the Ebola ‘lessons learned’ exercise is now in full swing. On our assessment, a significant shortcoming plagues recent articulations of lessons learned, particularly among those emerging from organizational reflections. In this (...) article we argue that, despite not being recognized as such, the vast majority of lessons proffered in this literature should be understood as ethical lessons stemming from moral failures, and that any improvements in future global public health emergency preparedness and response are in large part dependent on acknowledging this fact and adjusting priorities, policies and practices accordingly such that they align with values that better ensure these moral failures are not repeated and that new moral failures do not arise. We cannot continue to fiddle at the margins without critically reflecting on our repeated moral failings and committing ourselves to a set of values that engenders an approach to global public health emergencies that embodies a sense of solidarity and global justice. (shrink)

Ankeny et al. focuses on the recent creation of “iBlastoids” and defends the need for reflexive, anticipatory, and deliberative approaches in the domain of emerging and potentially contentio...

Localization and decentralization are frequently presented as good for women. However, the reality is not so clear cut. Local government is the tier that is closest to people, but relationships, structures, and processes of local governance can limit both the space for women’s participation and the policy potential for addressing gender issues. The experience of democratic reform in South Africa is invariably held up as an example of good practice in advancing gender equity in governance. Critically drawing (...) on this experience, the article points out some of the paradoxes for women and gender equity that arise from decentralization strategies and governance at the local level. (shrink)

The crisis in Kosovo has excited passion and visionary exaltation of a kind rarely witnessed. The events have been portrayed as "a landmark in international relations," opening the gates to a stage of world history with no precedent, a new epoch of moral rectitude under the guiding hand of an "idealistic New World bent on ending inhumanity." This New Humanism, timed fortuitously with a new millennium, will displace the crass and narrow interest politics of a mean spirited past. (...) Novel conceptions of world order are being forged, interlaced with inspirational lessons about human affairs and global society. (shrink)

What characterizes emergency today is the proliferation of the term. Any event or situation supposedly has the potential to become an emergency. Emergencies may happen anywhere and at any time. They are not contained within one functional sector or one domain of life. The substantive focus of the articles collected in this special issue reflects this proliferation: they explore ways of governing in, by and through emergencies across different types of emergencies and different domains of life. In response to this (...) proliferation, the issue opens up critical work on the politics of emergency beyond the ‘state of exception’ as dominant paradigm. Emergency is treated as a problem for government that calls for the invention of new techniques or the redeployment of existing techniques. Through this shift in emphasis, the articles in this issue disclose relations between modalities of power and emergency life that differ from the ‘lightening flash’ of a sovereign decision on the exception taken from outside of life, or the capacity to ‘mould’ an always-already emergent life from within life. (shrink)

South Africa has an education crisis, despite the fact that the government spends the biggest slice of its budget on education, more than any other African country. And yet the crisis persists. Jansen and Blank looked at South African schools that work, in spite of adverse conditions -- schools in poor communities, schools with overcrowded classrooms, schools in both rural and urban environments -- and have drawn out the practical strategies that make them successful. 19 short films (included on (...) DVD) let you visit these schools and understand in the words of their principals, teachers and learners what makes them succeed. Then take look at the 10 key strategies identified and see how to implement them in other schools to effect transformation. As we have come to expect from Jansen, there are no complicated theories, not difficult to implement solutions -- just lots of common sense! (shrink)

Clear, concise, and easy to read, this eye-opening book offers readers a walk through some of the greatest and most thought-provoking arguments from classical, modern, and contemporary philosophy. Along the path, it looks closely at: Socrates' answer to the question, "Did God create morality, or did he discover it?"; what Descartes meant when he said, "I think, therefore I am"; why Berkeley thought that matter and the material world don't really exist; an argument that shows that God necessarily (...) exists; whether we can really know anything at all; and finally, why (and whether) you owe any allegiance to the rules or laws of your government and society. An expert educator with more than twenty years' experience bringing these ideas to life for students, the author presents these influential, surprising philosophical arguments in a delightful and accessible way. While the topics span the four corners of western philosophy, the unifying theme here is one about philosophical skepticism, and how it's applied as a tool for greater intellectual inquiry. The book doesn't presuppose any familiarity with philosophy, though it certainly rewards those with a strong curiosity about big important ideas. After all, as Plato famously quipped, philosophy begins in wonder. (shrink)

Information Technology has ushered in not only large societal opportunities but also large uncertain ‐ ties and risks. Future developments, like ubiquitous networked embedded systems, are technologies society may face. Such technologies offer larger opportunities and uncertainties because of their ability to widely distribute power through their small, inexpensive, and ubiquitous characteristics. Many interpretations of how these technologies may develop have been postulated, ranging from the conservative Precautionary Principle, to uncontrolled development leading to “singularity.” With so much uncertainty and (...) so many predictions about the benefits and consequences of these technologies, it is important to raise ethical questions, determine potential scenarios, and try to identify appropriate decision points and stakeholders. Rather than going along an unknown path, perhaps lessons could be learned from recently deployed technologies, such as nuclear technology, that were controversial but offered similarly large potential benefits and risks. The experience of nuclear technology development, with its various successes and failures, is recalled and compared with potential scenarios in the development of networked embedded systems. (shrink)

In February 2019, the German federal government announced its new “National Industry Strategy 2030.” Many economies—including the United Kingdom (2017), European Union (2017), and Saudi Arabia (2018)—have announced national industrial strategies addressing the competitive threat of the People’s Republic of China’s 2015 “Made in China 2025” 5-year economic plan to become a global leader in 10 advanced technology manufacturing sectors. The use of the 20th-century term “industrial policy” heralds back to public policy antecedents of what is now evolving globally in (...) the 21st century as national “industrial strategy,” a concept explored in this article. Unlike traditional 20th-century efforts at industrial policy (which focused on public policy efforts to maintain domestic primacy of declining, older industries), national industrial strategy recognizes (and generally accepts) the international global economy as a foundation of competition. Most importantly, national industrial strategy focuses on technologically emerging industries as well as the national government working collaborative in a partnership with these emerging industries to meet future growth challenges and opportunities. (shrink)

This paper has two objectives 1) to study the influence of digital and new technology on COVID-19 diagnosis and healthcare 2) To propose the integral guideline solutions of the infectious disease for the future. COVID-19 stands for corona (CO), virus (VI), disease (D), or SARS-CoV-2, is a respiratory virus first identified in December 2019 in Wuhan, China(WHO, 2019). It is an epidemiological crisis that caused the deaths and sudden destruction of wealth and health of people around the world. Many (...) countries responded to the crisis with what could only be called urgent prevention and treatment. In the 21st century, our society is based on digital and new technology that can control and prevent the COVID-19 pandemics. However, these ways for solving the problem of COVID-19 pandemics are rising an epistemological crisis too. There are some problems with the COVID-19 diagnosis. From Buddhist philosophy perspective, COVID-19 teaches us the coronavirus is causing us to experience some heightened forms of the three marks of our existence which are the impermanence (aniccā), the suffering (duḥkha), and the non-self (anatta). The establishment of scientific expertise and innovation has shown its value and educating the public about testing, diagnosis, communication, treatment, and vaccine development technology for prevention the of infectious diseases in the future. (shrink)

The world is at an inflection point. Advancing technologies are creating new opportunities and challenges. Great demographic changes are occurring rapidly, with significant consequences. Governance everywhere is in disarray. A new world is emerging. These are some of the key insights to emerge from a series of interdisciplinary roundtables and global expert contributions hosted by the Hoover Institution. In these pages, George P. Shultz and James Timbie examine a range of issues shaping our present and (...) future, region by region. Concrete proposals address migration, reversing the decline of K-12 education, updating the social safety net, maintaining economic productivity, protecting our democratic processes, improving national security, and more. Meeting these transformational challenges will require international cooperation, constructive engagement, and strong governance. The United States is well positioned to ride this wave of change--and lead other nations in doing the same. (shrink)

In this article, we present a few lessons we learnt in the establishment of the Sciences Po médialab. As an interdisciplinary laboratory associating social scientists, code developers and information designers, the médialab is not one of a kind. In the last years, several of such initiatives have been established around the world to harness the potential of digital technologies for the study of collective life. If we narrate this particular story, it is because, having lived it from (...) the inside, we can provide an intimate account of the surprises and displacements of digital research. Founding the médialab in 2009, we knew that we were leaving the reassuring traditions of social sciences to venture in the unexplored territory of digital inscriptions. What we couldn't foresee was how much such encounter would change our research. Buying into gospel of Big Data, we imagined that the main novelty of digital research came from handling larger amounts of data. We soon realized that the interest of digital inscriptions comes instead from their proliferating diversity. Such diversity encouraged us to reshape our professional alliances, research practices and theoretical perspectives. It also led us to overcome several of the oppositions that used to characterize social sciences and to move in the direction of a more continuous sociology. (shrink)

There are three broad ethical issues related to handling public health emergencies. They are the three R's - rationing, restrictions and responsibilities. Recently, a severe shortage of annual influenza vaccine in the US, combined with the threat of pandemic flu, has provided an opportunity for policy makers to think about rationing in very concrete terms. Some lessons from annual flu vaccination likely will apply to pandemic vaccine distribution, but many preparatory decisions must be based on very rough estimates. (...) What ethical principles should guide rationing decisions, what data should inform these decisions, how to revise decisions as new data emerge, and how to implement rationing decisions on the ground are all important considerations. In addition, ethicists might be able to help policy makers think through the importance of international cooperation in surmounting global rationing dilemmas and to accept the inevitable responsibilities of government in making and implementing rationing decisions. (shrink)

As Edward Hundert--a philosopher, psychiatrist, and award-winning educator--makes clear in this eloquent interdisciplinary work, the newly emerging model for ...

Recent work on non-visual modalities aims to translate, extend, revise, or unify claims about perception beyond vision. This paper presents central lessons drawn from attention to hearing, sounds, and multimodality. It focuses on auditory awareness and its objects, and it advances more general lessons for perceptual theorizing that emerge from thinking about sounds and audition. The paper argues that sounds and audition no better support the privacy of perception’s objects than does vision; that perceptual objects are (...) more diverse than an exclusively visual perspective suggests; and that multimodality is rampant. In doing so, it presents an account according to which audition affords awareness as of not just sounds, but also environmental happenings beyond sounds. (shrink)

John Dewey’s role as a “public philosopher” is well-documented; his political activism, however, has not received much attention from philosophers. While Dewey is well remembered as a philosopher who escaped the walls of the academy to speak to and write for general audiences, he also lent his name, status, and intellectual energy to political organizations and movements in American politics. In the first part of the paper, I provide an introduction to Dewey’s activism and its relation to the philosophical (...) project of “democratization.” I consider present-day parallels between Dewey’s diagnosis of America’s political problems and the Bernie Sanders presidential campaign, as well as the structural and methodological challenges facing a Deweyan progressive politics. I conclude by advocating for a new conception of “public pragmatism” that reflects lessons learned and contemporary conditions for political activism by philosophers seeking to follow in Dewey’s footsteps. (shrink)

This contribution is a presentation of the encounter between Greek philosophy and Islam and of the way in which philosophical thought was consequently appropriated by the Muslim world. What made this encounter possible was the existence, within the Muslim world, of a spirit of openness able to overcome the fear of a ‘pagan’ thought: this spirit helped develop the position that Greek philosophy, qua wisdom, could not be ‘foreign’ to the universe of the Koran. The Arabic language, as (...) it became a philosophical language, bears traces of such an appropriation. Today, in Africa, the debate on philosophy could usefully take into account the tradition of Islamic philosophy which is also African to some extent and which would help enlighten, in particular, the question of transforming African tongues into philosophical languages. (shrink)

Two main methods for analysing de re readings of definite descriptions in intensional contexts coexist: that of evaluating the description in the actual world, whether by means of scope, actuality operators, or non-local world binding, and that of substituting another description, usually one expressing a salient or ‘vivid’ acquaintance relation to an attitude holder, prior to evaluation. Recent work on so-called descriptive indexicals suggests that contrary to common assumptions, both methods are needed, for different ends. This paper aims (...) to show that there is indeed a division of labour between the two methods of analysis and to identify criteria for choosing among alternative ways to model the second, substitutional method. (shrink)

There is never a shortage of celebratory and condemnatory popular discourse on digital media even in its early days. This, of course, is also true of the advent of Web 2.0. In this article, I shall argue that normative analyses of digital media should not take lightly the popular discourse, as it can deepen our understanding of the normative and axiological foundation(s) of our judgements towards digital media. Looking at some of the most representative examples available, I examine the latest (...) wave of popular discourse on digital media, focusing on the (new) worries and doubts voiced by the alarmists and the (new) hopes and dreams portrayed by the enthusiasts. I shall illustrate that various stances in the popular discourse on Web 2.0 are ultimately rested on different notions of the self. This conclusion entails an important lesson for our practice of critiques of digital media, as it entails that our critiques of digital media cannot be done without referring to a notion of the self. Hence, a normative enquiry of digital media should not only be about the moral and/or prudential goodness or badness per se; it should be about who we should be online, or which notion(s) of the self we should strive for. (shrink)

This paper addresses bioethics in the context of the coronavirus disease 2019 (COVID‐19) pandemic. The Introduction (Section 1) highlights that at the field's inception, infectiousness was not front and center. Instead, infectious disease was widely perceived as having been conquered. This made it possible for bioethicists to center values such as individual autonomy, informed consent, and a statist conception of justice. Section 2 urges shifting to values more fitting for the moment the world is in. To find these, it (...) directs attention to the Global South, and in particular, Africa, and to the values of ubuntu, solidarity, dignity, kinship, and humility. The paper concludes (in Section 3) that 21st‐century challenges facing bioethics are increasingly global, and calls on bioethicists themselves to be more globally inclusive in their approaches. (shrink)

A symposium on Samantha Frost’s Lessons from a Materialist Thinker: Hobbesian Reflections on Ethics and Politics offers an opportunity to revisit one of the most original contributions to Hobbes scholarship in the last few decades. The book’s originality resides not only in recuperating Hobbes’s materialist metaphysics for contemporary ethics and politics, but in making Hobbes’s take on matter inform novel conceptual approaches to social and non-social reality, such as new materialism – a philosophical school that conceives matter as (...) vibrant and agentic, rather than inert. (shrink)

This article uses a comparative approach to elucidate the ways in which women’s testimony operated in South Africa’s Truth and Reconciliation Commission and in Rwanda’s gacaca courts, to draw out some important lessons for future mechanisms of transitional justice. The author argues that while restorative justice mechanisms allow more space for including women’s own experiences of human rights violation than conventional trials, they may pose greater danger for those who testify. A significant problem resulting from the narratives (...) of both gacaca and the TRC is the way in which a ‘singular woman victim’ emerges that elides the complexity of women’s experiences in collective memory. It is feared that what has emerged from the official discourse of these two truth-seeking mechanisms is a one-dimensional female victim subject – in South Africa, she is of secondary importance, in Rwanda, she can only be Tutsi, and in both cases she is stripped of all agency, where rape becomes definitive of her experience. (shrink)

Much of the most substantive and in‐depth experience with formal cost‐benefit analysis in the public policy realm has occurred in the context of federal environmental regulation in the United States. This experience has many important lessons to teach in the realm of synthetic biology. Indeed, many of the dangers and pitfalls that arise when decision‐makers use formal CBA to evaluate environmental regulation seem likely to arise in the synthetic biology context as well, sometimes in particularly troubling forms. Unfortunately, while (...) in many instances these concerns may well point toward a rejection of formal CBA for synthetic biology, the experience from environmental regulation turns out to be far less helpful in identifying alternative decision‐making tools. Because the decisions that arise in the synthetic biology context have a fundamentally different structure from decisions about environmental regulation, the most useful alternatives from that context do not map easily onto this new context.It may well be generally true that in the search for decision‐making tools, we should not be looking for a single silver bullet that will work in all public policy realms. Perhaps, instead, different kinds of decision‐making call for different tools. This may be true even within the realm of synthetic biology. I am not entirely sure what the “right” tool is for synthetic biology applications, or even whether a “right” tool exists. But at the end of this essay, I offer a few tentative thoughts about why scenario analysis—a strategic planning tool first developed in the context of military planning following World War II—might be one alternative worth considering. (shrink)

Recent events around the globe reflect the tensions and ethical dilemmas of the postmodern, postcolonial and neocolonial world that have far reaching implications for health, well-being, and human suffering. As we consider what is at stake, and what this means for local lives and human relationships, we need to examine whether the theories we draw on are adequate to further our understanding of health, and the social and material conditions of human suffering. In this paper I begin to explore (...) the question, ‘Can postcolonial feminist theories provide an inclusive scholarship that would further our understanding of human suffering and open up a path to healing?’ At issue here is whether this scholarship adds another dimension to a praxis-oriented nursing science. (shrink)

Patient visitor restrictions were implemented in unprecedented ways during the COVID-19 pandemic and included bans on any visitors to dying patients and bans separating mothers from infants. These were implemented without high quality evidence they would be beneficial and the harms to patients, families and medical personnel were often immediately clear. Evidence has also accumulated finding strict visitor restrictions were accompanied by long-term individual and societal consequences. We highlight numerous examples of restrictions that were enacted during the COVID-19 pandemic, (...) including some that continue to be in place today. We outline six specific concerns about the nature and effects of the visitor restrictions seen during the COVID-19 pandemic. These considerations may help provide both an ethical and science-based framework, through which healthcare workers, families and government entities can work towards safeguarding patient and family rights and well-being. (shrink)

Brexit has been described as “probably the most disastrous single event in British history since the second world war.” (Wolf, 2016). This paper discusses three themes to emerge from Brexit (notions of democracy and populism, and the manipulation of digital technologies), and lessons that may be drawn from these for the rest of the Union, and the EU project more broadly.

Classic studies in human sensorimotor control use simplified tasks to uncover fundamental control strategies employed by the nervous system. Such simple tasks are critical for isolating specific features of motor, sensory, or cognitive processes, and for inferring causality between these features and observed behavioral changes. However, it remains unclear how these theories translate to complex sensorimotor tasks or to natural behaviors. Part of the difficulty in performing such experiments has been the lack of appropriate tools for measuring complex motor skills (...) in real-world contexts. Robot-assisted surgery (RAS) provides an opportunity to overcome these challenges by enabling unobtrusive measurements of user behavior. In addition, a continuum of tasks with varying complexity – from simple tasks such as those in classic studies to highly complex tasks such as a surgical procedure – can be studied using RAS platforms. Finally, RAS includes a diverse participant population of inexperienced users all the way to expert surgeons. In this perspective, we illustrate how the characteristics of RAS systems make them compelling platforms to extend many theories in human neuroscience, as well as, to develop new theories altogether. (shrink)

Thomas Hobbes is an iconic figure who serves as an easy reference for pundits commenting on the brutality of war as well as for critics of a distinctly modern individualism in which calculating and rapacious self-interest is the cause of the violence, destruction, and exploitation endemic to the contemporary world. Frost's reading of Hobbes's philosophy shows us that underlying such visions of self and politics is another iconic figure: that of the Cartesian subject. What gives the iconic Hobbes his (...) hardcore individualism and its corollary accounts of instrumentalism, conflict, and absolutism is a Cartesian rendering of the self as split into mind and body. Carefully elaborating Hobbes's materialist ontology, _Lessons from a Materialist Thinker_ challenges both our implicit Cartesian assumptions about the self and the commonplace Hobbes that so readily figures violence in our political imagination. Through his materialism, Hobbes presents an alternative modern account of self-consciousness, reason, agency, power, freedom, and responsibility. In doing so, he shows that our fundamental intersubjectivity and interdependence require that we pursue peace above all else. (shrink)

Fully grown Xenopus oocytes can remain in their immature state essentially indefinitely, or, in response to the steroid hormone progesterone, can be induced to develop into fertilizable eggs. This process is termed oocyte maturation. Oocyte maturation is initiated by a novel plasma membrane steroid hormone receptor. Progesterone brings about inhibition of adenylate cyclase and activation of the Mos/MEK1/p42 MAP kinase cascade, which ultimately brings about the activation of the universal M phase trigger Cdc2/cyclin B. Oocyte maturation provides an interesting example (...) of how signaling cascades entrain the cell cycle clock to environmental changes. BioEssays 21:833–842, 1999. © 1999 John Wiley & Sons, Inc. (shrink)

Government has come to mean governance. This article investigates this change, which, through an investigation of Foucault’s concept of governmentality, it will show to be a substantial modification of the concept of government.By the late 1970s, Foucault had begun to construct a political philosophy shorn of traditional power structures. He replaced these with the concept of governmentality, of which the “governmental rationality of liberalism” is one form. In this rationality, the government is no longer the final instance, but is (...) rather a process of structuring a field of action.Government ceases to be a specific method of organisation; the concept of governmentality is hence amorphous and is not limited to liberalism. But liberalism instituted a radical change: a hitherto unpracticed permeability between reasons of state and reasons of the market. Liberalism is characterised by frugal government. However, the check against excess in government does not emerge, as it did in other forms, through the rule of law or the balance of power of nations, both external to liberal rationality.Seeing the transactional economic model as the model of good governance, liberalism is frugal by its own nature. Unlimited economic productive power, necessary for the continuance of the liberal state, entails limited government, and anything that would limit economic transactions must limit from outside.Other rationalities, such as moral or judicial rationalities, are thus external to the nature of liberal rationality – they play no role in the only test liberalism uses to validate its actions: economic effect. This new rationality, which emerges in the middle of the 18th century as new concept of government, is the emergence of the political economy. (shrink)

After the end of the Cold War, many in the West viewed Africa as a testing ground for the solidarist argument that sovereignty was no longer an absolute principle and that the international community could intervene to protect individual from human rights violations. This argument seems particularly challenging in the African context, given the continental leadership’s historic commitment to territorial integrity and non-intervention. However, as the author shows, African leaders from 1945 to 1990 were largely upholding the (...) pluralist international norms of the time. In other words, the case for humanitarian intervention – and the problems posed by the practice – are not region-specific. The early 1990s, during which the United Nations intervened in Somalia, seemed to confirm the solidarist position. However, the failure to intervene in Rwanda in 1994, and the more recent experience of interventions in Sierra Leone, present a more mixed picture. Humanitarian intervention remains a controversial practice because of its coercive means, and its tendency to attribute blame or responsibility in what are often very complex civil conflicts. (shrink)

Analysing feminist responses to the (mainstream) media coverage of the sexual assaults of New Year’s Eve 2015 in Cologne, this article shows how a theoretical concept that is used to frame feminist arguments can influence the strength of those arguments. German-speaking media extensively reported on the large number of sexual assaults against women that happened during that night in Cologne. The dominant narrative in those media reports dwells on the circumstance that the arrested suspects all had a refugee or migrant (...) background, which assisted right-wing politics in re-creating a racist stereotype about male refugees and migrants being a threat to western women. Feminist responses to that media discourse insisted that rape culture was a cross-cultural phenomenon and that media as well as political analyses of the assaults need to take into account an understanding of intersectionality. Based on a content analysis of twenty-five feminist texts about the events of ‘Cologne’, I argue that the application of the concept of intersectionality created contradictions and argumentative voids within the – otherwise strong – feminist arguments because it conflated sexist and racist dynamics, which were both present in the context of ‘Cologne’ but not always intersecting. I further argue that these contradictions unintentionally aided the right-wing co-option of feminist demands concerning ‘Cologne’ and I suggest that the theoretical concept of femonationalism is better equipped to analyse events like ‘Cologne’. (shrink)

Global production networks connect multiple producers involved in fragmented manufacturing processes. Major brands and retailers, considered as lead firms, are under increasing pressure to ensure products made through GPNs are produced sustainably. Theories of governance developed to understand dynamics in outsourced production can provide insight into this issue. However, these theories and related empirical research have often focused on relationships between lead firms and upper-tier suppliers. When manufacturing involves multiple fragmented stages, understanding the role of lead firms becomes more (...) difficult. This article considers new governance roles that lead firms, as buyers, are playing when attempting to promote sustainable practices across all stages of production for buyer-driven industries. The focus is exploring the nature of new governance approaches which lead firms have developed in order to address diverse sustainability challenges found within GPNs, particularly related to lower-tier suppliers. These approaches can involve lead firms working through vertical buyer–seller links or developing new horizontal relationships, which link lead firms with lower-tier suppliers and governance processes in these suppliers’ local productive systems. The findings draw from field research examining how top UK garment retailers provide governance to producers involved in creating cotton garments in India and a review of publicised policies and practices of these retailers related to promoting sustainable production. Five types of governance mechanisms that can involve vertical or horizontal links are identified. Considering the growth of new governance relationships expands previous conceptions of the roles of lead firm governance. (shrink)

Alexander Bird argues for an epistemic account of scientific progress, whereas Darrell Rowbottom argues for a semantic account. Both appeal to intuitions about hypothetical cases in support of their accounts. Since the methodological significance of such appeals to intuition is unclear, I think that a new approach might be fruitful at this stage in the debate. So I propose to abandon appeals to intuition and look at scientific practice instead. I discuss two cases that illustrate the way in which scientists (...) make judgments about progress. As far as scientists are concerned, progress is made when scientific discoveries contribute to the increase of scientific knowledge of the following sorts: empirical, theoretical, practical, and methodological. I then propose to articulate an account of progress that does justice to this broad conception of progress employed by scientists. I discuss one way of doing so, namely, by expanding our notion of scientific knowledge to include both know-that and know-how. (shrink)

Bowman-Smart et al. (2023) sketched a hypothetical scenario involving noninvasive prenatal testing (NIPT) for “non-medical” traits available for expectant parents in the near future. By critically...

Thucydides excuses the possible dullness of his history on the ground that he means it not for a passing entertainment but for a ‘permanent possession’ which may be of practical use in future times when some similar situation occurs again. We tend to smile at the idea. We all know that history never repeats itself. But surely we know also that though exactly the same situation or problem never recurs, yet elements are constantly recurring which, in different contexts, with all (...) sorts of different accompaniments, are essentially the same; and though, obviously, the old parallel never provides an answer to the new problem, it may well help to its understanding. The differences between any problem of ours and those of Thucydides are of course enormous. Our civilisation, immense in scale, dazzling in its scientific inventions and its power over matter, is extremely different from the small-scale city state of fifth-century Athens with no electricity, no gas, no steam, no buttons, no drainage even, and a standard of food and comfort which would produce instantaneous strikes in any Western community. Yet the essential situation which Thucydides had to face was the overthrow of a very high and peculiar civilisation by a long and all-absorbing war, a war to which men could find no end, from which they could never keep aloof, and under whose influence they found themselves sinking to standards of barbarism which filled them with horror. We in modern Europe share the experience of that sort of war; and we share perhaps more fully than any age between that time and our own the special quality of that civilisation. How can we find words to describe it? It was a free civilisation, proud of its freedom of life and thought, its advance in knowledge, art, literature; with flourishing commerce, with wide command of the sea, with an acknowledged superiority over ‘barbaric’ or non-Greek communities and over some that were Greek; and open, evidently, to the kind of criticism that is always provoked by a combination of commercial wealth and high culture, of democracy and empire. Thucydides has left us a wonderful picture of Athens, not of course exactly as she was but as she conceived herself to be or as she was in the eyes of those who loved her. It is not quite as we now see her; to us, living two thousand years afterwards, Athens is chiefly remarkable for its ever-living achievements in art, philosophy, and poetry; but Thucydides hardly mentions such things, though in one famous half-sentence, ‘We seek beauty without luxury’, he doubtless implies them. He writes not as a critic of art or poetry; and his philosophy is only the philosophy of a statesman. (shrink)

Among many properties distinguishing emergence, such as novelty, irreducibility and unpredictability, computational accounts of emergence in terms of computational incompressibility aim first at making sense of such unpredictability. Those accounts prove to be more objective than usual accounts in terms of levels of mereology, which often face objections of being too epistemic. The present paper defends computational accounts against some objections, and develops what such notions bring to the usual idea of unpredictability. I distinguish the objective unpredictability, compatible with determinism (...) and entailed by emergence, and various possibilities of predictability at emergent levels. This makes sense of practices common in complex systems studies that forge qualitative predictions on the basis of comparisons of simulations with multiple values of parameters. I consider robustness analysis as a way to ensure the ontological character of computational emergence. Finally, I focus on the property of novelty, as it is displayed by biological evolution, and ask whether computer simulations of evolution can produce the same kind of emergence as the open-ended evolution attested in Phanerozoic records. (shrink)

Nanomedicine plays a prominent role among emerging technologies. The spectrum of potential applications is as broad as it is promising. It includes the use of nanoparticles and nanodevices for diagnostics, targeted drug delivery in the human body, the production of new therapeutic materials as well as nanorobots or nanoprotheses. Funding agencies are investing large sums in the development of this area, among them the European Commission, which has launched a large network for life-sciences related nanotechnology. At the same time (...) government agencies as well as the private sector are putting forward reports of working groups that have looked into the promises and risks of these developments. This paper will begin with an introduction to the central ethical themes as identified by selected reports from Europe and beyond. In a next step, it will analyse the most frequently invoked ethical concerns–risk assessment and management, the issues of human identity and enhancement, possible implications for civil liberties (e.g. nanodevices that might be used for covert surveillance), and concerns about equity and fair access. Although it seems that the main ethical issues are not unique to nanotechnologies, the conclusion will argue against shrugging them off as non-specific items that have been considered before in the context of other biomedical technologies, such as gene therapy or xenotransplantation. Rather, the paper will call on ethicists to help foster a rational, fair and participatory discourse on the different potential applications of nanotechnologies in medicine, which can form the basis for informed and responsible societal and political decisions. (shrink)

Many scientists have expressed concerns about potential catastrophic risks associated with new technologies. But expressing concern is one thing, identifying serious candidates another. Such risks are likely to be novel, rare, and difficult to study; data will be scarce, making speculation necessary. Scientists who raise such concerns may face disapproval not only as doomsayers, but also for their unconventional views. Yet the costs of false negatives in these cases -- of wrongly dismissing warnings about catastrophic risks -- are by definition (...) very high. For these reasons, aspects of the methodology and culture of science, such as its attitude to epistemic risk and to unconventional views, are relevant to the challenges of managing extreme technological risks. In this piece I discuss these issues with reference to a real-world example that shares many of the same features, that of so-called 'cold fusion'. (shrink)

Recent work on skin-brain thesis suggests the possibility of empirical evidence that empiricism is false. It implies that early animals need no traditional sensory receptors to be engaged in cognitive activity. The neural structure required to coordinate extensive sheets of contractile tissue for motility provides the starting point for a new multicellular organized form of sensing. Moving a body by muscle contraction provides the basis for a multicellular organization that is sensitive to external surface structure at the scale of the (...) animal body. In other words, the nervous system first evolved for action, not for receiving sensory input. Thus, sensory input is not required for minimal cognition; only action is. The whole body of an organism, in particular its highly specific animal sensorimotor organization, reflects the bodily and environmental spatiotemporal structure. The skin-brain thesis suggests that, in contrast to empiricist claims that cognition is constituted by sensory systems, cognition may be also constituted by action-oriented feedback mechanisms. Instead of positing the reflex arc as the elementary building block of nervous systems, it proposes that endogenous motor activity is crucial for cognitive processes. In the paper, I discuss the issue whether the skin-brain thesis and its supporting evidence can be really used to overthrow the main tenet of empiricism empirically, by pointing out to cognizing agents that fail to have any sensory apparatus. (shrink)

In her 2002 essay, "Anthropocentrism, Artificial Intelligence, and Moral Network Theory: An Ecofeminist Perspective," Victoria Davion points out, utilizing Val Plumwood's ecofeminist analysis, the faulty anthropocentric, logocentric assumptions made both within the artificial intelligence (AI) community, generating serious problems in the effort to build "intelligent" machines, and in moral philosophy, its "rule-based picture of moral reasoning" (169) coming under fire from the emerging field of neural net research. Davion demonstrates prescience regarding the direction in which both disciplines eventually (...) move, as they learn important "lessons from nature": that intelligence and moral reasoning are widely distributed throughout the Biosphere and are _not_ based upon what has been taken as paradigmatic—the reductive, linear logic, abstracted from all context, characteristic of only one possible way of approaching the world. I present updates regarding artificial intelligence, neuropsychology, and the philosophical analysis of anthropocentrism, affirming that directing open, respectful attention toward the Other in the real, living world will eventually provide us with the ontological foundation for a nonanthropocentric ethics capable of sustaining truly intelligent and moral ways of living. (shrink)

Relative price stability is central to the security of valued forms of life in contemporary liberal democracies, and disruptions to price stability can be and have been understood and experienced as emergencies. However, while the relation between price and emergency can be understood in juridico–political terms, this article argues for the importance of attending to the affective dimensions of this relation. This argument is developed through a discussion of the affective life of price in relation to the disruptive event of (...) inflation, an event characterized by an atmosphere of emergency that takes place as a disturbance of the rhythms and relations of which everyday life consists. Haunted by the spectre of this emergency, governing price in liberal democracies needs to be understood not only through regulatory measures designed to act directly upon price, but also in terms of efforts to act upon the affective spacetimes from which price-emergencies can emerge. (shrink)